Translational Gynaecology

• Determine the biological mechanisms that underpin the symptom of abnormal uterine bleeding (AUB), including heavy menstrual bleeding (HMB).
• Provide earlier diagnosis of the underlying causes (including uterine fibroids and adenomyosis) of AUB/ HMB.
• Optimise treatments for AUB/HMB and to make them personalised, more effective, and with fewer side effects

HOPE is a website all about periods and menstrual health. It provides accurate, accessible information for those who menstruate, their families, doctors, employers and policy makers. In addition, the website provides resources for educators to facilitate the conversation about menstruation with both boys and girls at a young age to increase awareness and destigmatise this physiological process. 

• Improve our understanding of the mechanisms that contribute to the aetiology of endometriosis
• Understand why symptoms vary between individuals
• Develop and accumulate information that can inform personalised approaches to symptom management. 

EXPPECT brings together individuals involved in the clinical care of women with pelvic pain and endometriosis with discovery and data scientists, to form a hub within which innovative approaches to pelvic pain treatment can be developed in collaboration with commercial partners.

• Better understand the preventable drivers of gynaecologic cancers to stop their development at the earliest stage
• Create novel, minimally invasive or non-invasive diagnostic methods to detect these malignancies and precursors early
• Better characterise and understand the tumour microenvironments of endometrial, ovarian, and breast cancer

• Enable ‘real’ reproductive autonomy through quality understandable information on options for avoiding unintended pregnancy as well as overcoming barriers to accessing quality contraception care, especially after pregnancy.
• Expand contraception options with new, effective methods with fewer side effects and more health benefits. This includes on demand contraception an methods which work after ovulation. 

Our diverse faculty, consisting of scientists, clinician-scientists, trialists, and health service researchers, enables us to translate research from bench to bedside and beyond. We have strong integration with NHS Lothian, ensuring that our findings are directly relevant to clinical practice. Public and patient engagement is fundamental to our research and its impact on healthcare and society. 

Gynaecology - NHS Lothian

We collaborate across disciplines and sectors to investigate epidemiology, risk factors, and the underlying molecular and cellular mechanisms of gynaecologic diseases. By working closely with various scientific, clinical, and public health experts, we aim to foster synergies that lead to innovative solutions and improved health outcomes. Additionally, we study behavioural and complex interventions to empower individuals to make informed health choices.

CRH centre partnerships