Rosario group

Ovarian biology and female fertility

Female fertility is finite and declines as women age. We are interested in understanding how human eggs are made during fetal life and processes that underpin their loss in adult life, to identify ways to protect and preserve female fertility against unwanted harmful effects of specific medications and environmental exposures.

Dr Roseanne Rosario

Principal Investigator

  • Centre for Reproductive Health
  • Institute for Regeneration and Repair

Contact details

Research interests

  • Establishment of the human ovarian reserve and dynamics surrounding follicle loss
  • Signalling pathways important in governing primordial follicle activation
  • Effects of chemotherapy on the human ovary and methods for chemoprotection
  • Immune cells and their role in ovarian reserve maintenance
  • Exploration of putative oogonial stem cells
Rosario infographic for ovvarian oocyte production

Group Members

Vlastimil Srsen, Postdoctoral Research Scientist

Emily Walshe, PhD student

Publications

 

Collaborators

Prof Richard Anderson

Prof Evelyn Telfer

Prof Ian Adams

Dr Douglas Gibson

Prof Karla Hutt

Prof Susana Chuva De Sousa Lopes

Funders

Academy of Medical Sciences

Tenovus Scotland

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