GaPP2

GaPP2 is a multi-centre randomised controlled trial of the efficacy of action of gabapentin for the management of chronic pelvic pain in women

GaPP2 is a multi-centre, double blind randomised controlled trial of the efficacy of action of gabapentin for the management of chronic pelvic pain in women. Chronic pelvic pain affects >1 million women in the UK.
 
The aim of GaPP2 trial is to assess whether gabapentin has the potential to provide a safe, effective and convenient oral treatment and to prove if it can alleviate pain, and improve quality of life in women with chronic pelvic pain in the absence of no obvious pelvic pathology. It also has an embedded mechanistic study using functional MRI of the brain to determine the mechanism of action of gabapentin.